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Cardiac Troponin I (cTnI) is a cardiac muscle protein with a molecular weight of 22.5 kDa. In the heart it forms a protein complex together with Troponin T and C. The troponin complex is broken up following myocardial damage, and the individual protein components are released into the bloodstream. Although Troponin I is also found in skeletal muscles, this form differs from cTnI in its amino acid composition. This distinction allows the two forms of Troponin I to be distinguished immunologically and thereby ensures an accurate test assay. cTnI is released to blood circulation soon after the onset of cardiac damage. Approximately 4 to 6 hours following an acute myocardial infarction (AMI), a detectable level of cTnI can be detected with our immunochromatographic test. While the normal serum level of cTnI is below 0.06ng/ml, levels as high as 100-1300ng/ml in some AMI patients.
