D-Dimer is a protein fragment (small piece) that’s made when a blood clot dissolves in your body. Blood clotting is an important process that prevents you from losing too much blood when you are injured. Normally, your body will dissolve the clot once your injury has healed.
The concentration of D-Dimer in human plasma can be directly determined by utilizing the interaction of antigen and antibody. When we add sample to the latex particles coated with rabbit anti-human D-dimer antibody, insoluble complex is formed. The agglutination causes an absorbance change, dependent upon the D-Dimer contents of the patient sample that can be quantified by comparison from a calibrator of known D-Dimer concentration