Principle :
Dengue is spread by several species of mosquito of the Aedes type, principally A. aegypti. The virus has five different types;infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. Dengue is considered to be the most important arthropod‐borne viral disease due to the human morbidity and mortality it causes. Traditionally, the serological diagnosis of an acute dengue virus infection has relied on showing a 4‐fold or greater rise in anti-dengue virus antibody between paired acute and convalescent phase sera from a patient. A number of tests are available to confirm the diagnosis including detecting antibodies to the virus or its RNA.
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